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Early Phase 1
Age: 18Years +
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ID07400471

Study of Preemptive Multimodal Pain Relief Using Pregabalin and Duloxetine with Acetaminophen for Pain After Root Canal Treatment

Led by Chattogram International Dental College · Updated on 2026-02-11

280

Participants Needed

1

Research Sites

4 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of preemptive multimodal analgesics compared to placebo in managing immediate and chronic pain following root canal therapy, known as post-endodontic pain. This early phase 1 clinical trial uses statistical methods like chi-squared tests and regression analysis, including adjustments for multiple outcomes. The study tests two drugs available in Bangladesh, duloxetine hydrochloride and pregabalin, alongside placebos to assess both drug and psychological effects on pain. Ethical standards follow international guidelines.

CONDITIONS

Brief Title

The Effects of Preemptive Multimodal Analgesic on Endodontic Pain Following Root Canal Therapy.

Research Team

P

Prof.Dr. Md. Abu Saeed Ibn Harun, MS

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