Actively Recruiting

Age: 13Years - 15Years
All Genders
NCT06165952

Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning

Led by Stanford University · Updated on 2026-04-24

162

Participants Needed

1

Research Sites

229 weeks

Total Duration

On this page

Sponsors

S

Stanford University

Lead Sponsor

U

University of North Carolina, Chapel Hill

Collaborating Sponsor

AI-Summary

What this Trial Is About

Examine if ultra-processed (UP) foods are more effective in activating reward, attention, and memory brain regions and in promoting food cue learning than minimally-processed foods. Assess individual differences in neurobehavioral responses to UP foods.

CONDITIONS

Official Title

Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning

Who Can Participate

Age: 13Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Female and male adolescents aged 13 to 15 years
  • Age- and sex-adjusted BMI scores between the 25th and 75th percentile
  • Participant and guardian must be able to read and speak English to provide valid consent
Not Eligible

You will not qualify if you...

  • Current eating disorders or major psychiatric disorders such as depression, bipolar disorder, schizophrenia, or substance use disorder
  • Contraindications for fMRI such as metal implants, braces, claustrophobia, or pregnancy
  • Serious medical conditions including Type 2 diabetes or cancer
  • History of food allergies or restrictive dietary diets like lactose intolerance or veganism
  • Use of psychoactive drugs more than once weekly
  • Use of medications affecting appetite or reward functions, e.g., metformin, antipsychotic medication, insulin

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stanford University

Stanford, California, United States, 94305

Actively Recruiting

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Research Team

E

Eric Stice, PhD

CONTACT

T

Teena Ambrose, BS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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