Actively Recruiting
Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures
Led by Masonic Cancer Center, University of Minnesota · Updated on 2026-02-04
30
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
Sponsors
M
Masonic Cancer Center, University of Minnesota
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Characterize effects of relighting on smoke toxicant deliveries and subjective smoking measures. This will be a within-subject comparison in a single experimental group of 30 smokers who report engaging in relighting behaviors. We will assess smoking intensity for relit and non-relit (i.e., smoked continuously without relighting) cigarettes in the natural environment and will conduct in-clinic measurements of smoking topography and subjective responses for relit and non-relit cigarettes. Information on relighting patterns and smoking topography collected from each participant will be used to compare machine-measured smoke yields of key harmful constituents when their usual cigarettes are smoked with and without relighting. Hypothesis: Relit cigarettes will produce higher levels of toxicants than non-relit cigarettes.
CONDITIONS
Official Title
Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Smoking at least 10 cigarettes per day for at least 1 year, confirmed by CO > 8 ppm or NicAlert test of 6
- Engaging in relighting for at least half of their cigarettes smoked per day
- No quit attempts in the past month nor plans to quit in the next month
- Stable medical or psychiatric conditions with systolic blood pressure < 160, diastolic blood pressure < 100, and heart rate < 105 bpm
You will not qualify if you...
- Current or recent alcohol or drug abuse problems, or use of substances of abuse (other than marijuana) within the past month
- Currently trying or planning to quit smoking in the next month
- Planning to become pregnant, pregnant, or breastfeeding (pregnancy exclusion confirmed by urine test)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Irina Stepanov, PhD
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
Research Team
I
Irina Stepanov, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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