Actively Recruiting

Phase 4
Age: 2Years - 12Years
All Genders
NCT07118579

Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy

Led by Tongji Hospital · Updated on 2025-11-21

114

Participants Needed

1

Research Sites

44 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To observe the effects of remimazolam versus ciprofol TIVA on PRAE in pediatric tonsillectomy and adenoidectomy.

CONDITIONS

Official Title

Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy

Who Can Participate

Age: 2Years - 12Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 2-12 years
  • ASA physical status I-II
  • Body mass index (BMI): 14-28 kg/m8
  • Scheduled for elective tonsillectomy with or without adenoidectomy
  • Signed informed consent by legal guardian(s) and assent by children (68 years old)
Not Eligible

You will not qualify if you...

  • History of severe pulmonary diseases (e.g., asthma, bronchiectasis, severe OSA)
  • Previous episodes of significant perioperative respiratory adverse events
  • Documented drug allergies (e.g., to remimazolam, propofol, or ciprofol)
  • Comorbidities including uncorrected congenital heart disease, neuromuscular disorders, developmental delay, abnormal hepatic or renal function
  • Preoperative moderate-to-severe respiratory infections requiring surgery postponement
  • Recent participation in other clinical trials

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tongji Hospital

Wuhan, Hubei, China, 430030

Actively Recruiting

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Research Team

P

Pu Zhou

CONTACT

A

Aihua Du

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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