Actively Recruiting

Phase Not Applicable
Age: 50Years - 65Years
FEMALE
NCT06538454

Effects of Resistance Training Intensity on Cardiovascular Parameters of Hypertensive Women

Led by University of Sao Paulo · Updated on 2024-08-05

24

Participants Needed

1

Research Sites

57 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to understand about the effects of resistance training (RT) intensity on cardiovascular parameters in postmenopausal women with systemic arterial hypertension (SAH). The main research questions are: * Does the intensity of RT impact blood pressure (BP) in postmenopausal women with SAH? * How does RT intensity affect heart rate (HR) and their variability (HRV), endothelial function (EF), and nitric oxide (NO) biomarker synthesis in this population? * What are the effects of RT intensity on affectivity and rate of perceived exertion (RPE)? Researchers will compare two different intensities of RT (60% of the load for 1 repetition maximum \[1RM\] and 80% of 1RM) to determine their effects on the mentioned cardiovascular and perceptual parameters. Participants will: In the acute experiment: * Perform the same RT session in a crossover design, training with 60% of 1RM in one condition and 80% of 1RM in another condition * Have BP, HR, and HRV measured before, immediately after, and for one hour post-session * Report affectivity before each session and at the end, along with RPE In the chronic experiment: * Be randomized into two groups: one training with 60% of 1RM and the other with 80% of 1RM * Undergo a 10-week intervention period with evaluations before, during, and after the intervention * Have BP, HR, affective responses, and RPE measured at multiple time points * Have EF, HRV, and salivary concentrations of NO biomarkers assessed before and after the intervention

CONDITIONS

Official Title

Effects of Resistance Training Intensity on Cardiovascular Parameters of Hypertensive Women

Who Can Participate

Age: 50Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 50 to 65 years
  • Postmenopausal diagnosis with amenorrhea for 12 months or more
  • Previous diagnosis of hypertension and currently treated with medications
  • Physically inactive
Not Eligible

You will not qualify if you...

  • History of other cardiovascular problems such as heart failure, heart attack, or stroke
  • Grade II obesity with BMI equal to or greater than 35 kg/m²
  • Use of beta-blockers and/or non-dihydropyridine calcium channel blockers
  • Resting systolic blood pressure above 160 mmHg or diastolic blood pressure above 105 mmHg
  • Unable to perform resistance exercise due to musculoskeletal or cognitive reasons

AI-Screening

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Trial Site Locations

Total: 1 location

1

Laboratório de Fisiologia do Exercício e Metabolismo

Ribeirão Preto, São Paulo, Brazil

Actively Recruiting

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Research Team

L

Leonardo S Gonçalves

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Effects of Resistance Training Intensity on Cardiovascular Parameters of Hypertensive Women | DecenTrialz