Actively Recruiting
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure
Led by Kieu Nguyen Dang Phuong · Updated on 2026-04-30
146
Participants Needed
2
Research Sites
157 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
CONDITIONS
Official Title
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 60 years or older
- Meet the 2019 AWGS2 diagnostic criteria for sarcopenia based on muscle mass, handgrip strength, or walking speed
- Diagnosed with heart failure according to ESC 2021 criteria
- Able to understand the study and provide informed consent
You will not qualify if you...
- Early stage after acute coronary syndrome (within 2 days)
- Unstable coronary artery disease
- Decompensated heart failure
- Acute venous thrombosis or recent arterial embolism
- Acute myocarditis, pericarditis, or endocarditis
- Aortic dissection or severe symptomatic aortic stenosis
- Acute systemic disease or fever
- Uncontrolled or life-threatening atrial or ventricular arrhythmias
- Uncontrolled tachycardia (resting heart rate > 120 bpm)
- Third-degree AV block
- Uncontrolled diabetes
- Symptomatic orthostatic hypotension (> 20 mmHg)
- Increasing fatigue or dyspnea at rest or exertion within past 3-5 days
- Significant myocardial ischemia at low workloads (< 2 METs or 50W)
- Weight gain 61.8 kg in past 1-3 days
- Use of continuous or intermittent Dobutamine
- Decrease in blood pressure with exercise
- NYHA IV heart failure
- Complex ventricular arrhythmias at rest or with exertion
- Resting heart rate 61 100 bpm when lying down
- Comorbidities limiting exercise
- Severe obstructive hypertrophic cardiomyopathy
- Participation in cardiovascular rehabilitation within last 6 months
- Declines to participate in the study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Military Hospital 175
Ho Chi Minh City, Vietnam, 700000
Actively Recruiting
2
University of Medicine and Pharmacy at Ho Chi Minh City
Ho Chi Minh City, Vietnam, 700000
Actively Recruiting
Research Team
N
Nguyen Dang P Kieu, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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