The effect of high-sodium and low-sodium intakes on blood pressure and other related variables in human subjects with idiopathic hypertension.
T Kawasaki, C S Delea, F C Bartter...
https://pubmed.ncbi.nlm.nih.gov/629267Completed
All Genders
Healthy Volunteers
ID00001176
The Function of Dopaminergic and Noradrenergic Systems in Salt-Sensitive Hypertension: The Effects of Changes in Sodium Intake
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2008-03-04
110
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Some patients with high blood pressure can experience an increase of blood pressure by 10 percent or more by taking in salt. These patients are referred to as having "salt-sensitive" (SS) hypertension. Previous studies conducted on patients with salt sensitive hypertension suggest that their portion of the nervous system responsible for maintaining normal blood pressure (autonomic nervous system) may respond differently to salt than patients with non-salt sensitive (NSS) hypertension. This study is designed to examine the response of the nervous system to high doses of salt in patients with salt-sensitive hypertension and patients with non-salt sensitive hypertension.
CONDITIONS
Official Title
Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure
Who Can Participate
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
Eligibility criteria not identified in protocol.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
National Heart, Lung and Blood Institute (NHLBI)
Bethesda, Maryland, United States, 20892
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Factors influencing blood pressure in salt-sensitive patients with hypertension.
T Fujita, W L Henry, F C Bartter...
https://pubmed.ncbi.nlm.nih.gov/6998291Effects of dietary sodium and of acute saline infusion on the interrelationship between dopamine excretion and adrenergic activity in man.
R W Alexander, J R Gill, H Yamabe...
https://pubmed.ncbi.nlm.nih.gov/4600048