Actively Recruiting

Phase Not Applicable
Age: 30Years - 65Years
FEMALE
ID06737926

Effects of Sensorimotor Training on Pain Intensity, Perceived Balance Confidence and Functional Exercise Capacity in Breast Cancer Patients with Chemotherapy-Induced Peripheral Neuropathy

Led by Riphah International University · Updated on 2024-12-17

24

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of sensorimotor training on pain intensity, perceived balance confidence, and functional exercise capacity in female breast cancer patients experiencing chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a common side effect of chemotherapy, causing sensory and motor symptoms in 30-70% of cases. This study aims to understand how targeted exercise interventions may help manage these symptoms in women diagnosed with invasive ductal carcinoma stages I-III who have completed chemotherapy treatment and are medically stable. The trial is a single-blinded randomized controlled study involving 22 participants divided into two groups. One group performs sensorimotor training with progressively challenging balance exercises on unstable surfaces for 45 minutes twice a week over 6 weeks. The other group receives conventional exercise therapy including range of motion, stretching, strengthening, deep breathing, and aerobic exercises with the same frequency and duration. Both interventions are supervised and aim to improve balance, reduce pain, and enhance functional exercise capacity. Participants undergo assessments before and after the 6-week intervention. Evaluations include the Numeric Pain Rating Scale for pain intensity, the Timed Up and Go (TUG) test for balance, the Activities-Specific Balance Confidence Scale for perceived balance confidence, and the 6-Minute Walk Test for functional exercise capacity. Additional measures include quality of life questionnaires and neurological tests. The study tracks improvements in these areas to assess the impact of sensorimotor training compared to conventional therapy.

CONDITIONS

Brief Title

Effects of Sensorimotor Training With Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Patients

Who Can Participate

Age: 30Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female with invasive ductal carcinoma, stages I to III
  • Aged between 30 and 65 years
  • 3 to 6 months post breast cancer diagnosis
  • Completed chemotherapy treatment and medically stable
  • Experiencing chemotherapy-induced peripheral neuropathy symptoms as assessed by FACT/GOG-Ntx score
  • Balance impairment with Fullerton Advanced Balance scale score of 25 or less
  • Able to undergo neurological testing including tendon reflexes, sensitivity, position sense, and leg strength assessments
Not Eligible

You will not qualify if you...

  • Presence of other types of cancer besides breast cancer
  • Chronic medical conditions like poorly controlled diabetes
  • Significant neurological diseases such as multiple sclerosis
  • Cardiopulmonary disease including recent myocardial infarction within 3 months
  • Unstable bone metastasis

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Outpatient Treatment

Duration - 6 weeks

Participants perform sensorimotor training or conventional exercise therapy aimed at improving balance, reducing pain intensity, and enhancing functional exercise capacity. Sessions occur twice a week for 6 weeks, each lasting about 45 minutes.

Twice-weekly sessions for 6 weeks

Trial Site Locations

Total: 2 locations

1

Mayo Hospital Lahore

Lahore, Punjab Province, Pakistan, 54000

Actively Recruiting

2

Mayo Hospital

Lahore, Punjab Province, Pakistan, 54000

Actively Recruiting

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Research Team

I

Imran Amjad, PHD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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