Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery on Airway Plateau Pressure: a Randomized, Prospective, Blinded Pilot Study

What this Trial Is About

Researchers are evaluating the effects of two inhalational anesthetics, sevoflurane and desflurane, during robotic-assisted abdominal surgery. The study focuses on how these anesthetics influence lung mechanics, particularly airway plateau pressure, under protective mechanical ventilation. This comparison is important because inhalational anesthetics may offer lung protection and reduce inflammation during surgery, yet little is known about their differences in this surgical setting. Participants will receive either sevoflurane or desflurane anesthesia while undergoing elective robotic-assisted abdominal surgery. Both anesthetics are volatile agents administered during the procedure, with patients randomly assigned to one of these two treatment groups. The study is conducted as a randomized, prospective, and triple-blinded pilot trial to carefully assess the effects of each anesthetic. During the surgery, researchers will monitor airway plateau pressure to understand lung mechanics under each anesthetic. Patient evaluations include perioperative measurements related to respiratory function. The trial spans from the preparation before surgery through the procedure itself, with safety and lung function outcomes assessed during this time. Participants will be followed until the completion of their surgical and immediate postoperative period to collect relevant data.

Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery