Actively Recruiting
Effects of Step Training in Older Adults with Mild Dementia
Led by The Hong Kong Polytechnic University · Updated on 2025-03-13
145
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
T
The Hong Kong Polytechnic University
Lead Sponsor
U
University Grants Committee, Hong Kong
Collaborating Sponsor
AI-Summary
What this Trial Is About
Step training has been shown to be effective at reducing the incidence of falls and improving related risk factors, including choice stepping, in healthy older adults. However, the effects of step training have not been investigated in OWMD. The primary objective of the proposed project will be to assess the effects of a step-training program involving concurrent stepping and visuospatial tasks on choice stepping, prefrontal cortex functioning during choice stepping, and fall-related outcomes (i.e., step length, lower-limb muscle strength, balance, mobility, dual-task ability, and fear of falling) in OWMD. The prefrontal cortex is responsible for the executive functions such as attention and inhibitory function, which are integral to choice stepping reaction time tasks. However, the effects of step training on prefrontal cortex functioning during choice stepping in OWMD remain unclear. The neural mechanisms underlying the potential effects of step training on choice stepping have never been investigated in this population. Therefore, the secondary objective of the proposed project will be to evaluate the mediating effects of changes in the prefrontal cortex functioning during choice stepping on the potential benefits of a step-training program for choice stepping in OWMD. The proposed project will provide robust evidence to support the use of step training to improve choice stepping and reduce the risk of falls in OWMD. Disentangling the neural mechanisms underlying the effects of step training will be crucial to the development of the most effective interventions to target these mechanisms.
CONDITIONS
Official Title
Effects of Step Training in Older Adults with Mild Dementia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 65 years old
- Have a physician's diagnosis of dementia according to the Diagnostic and Statistical Manual of Mental Disorders 5th edition
- Have mild dementia with a score of 10 or higher on the Montreal Cognitive Assessment Hong Kong version
- Able to walk 10 meters independently without a walking aid
- Receiving care from an unpaid main caregiver with at least 3.5 hours of face-to-face contact per week
You will not qualify if you...
- Unable to perform step training due to unstable or severe musculoskeletal, cardiorespiratory, or neurological conditions
- Have severe hearing and/or visual impairments that limit communication ability
- Have been hospitalized within the past 30 days
AI-Screening
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Trial Site Locations
Total: 1 location
1
The Hong Kong Polytechnic University
Hong Kong, Hong Kong
Actively Recruiting
Research Team
W
Wayne LS Chan, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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