Effects of strength training on the incidence and progression of knee osteoarthritis.
Alan E Mikesky, Steven A Mazzuca, Kenneth D Brandt...
https://pubmed.ncbi.nlm.nih.gov/17013851Completed
Phase 2
Age: 60Years +
All Genders
Healthy Volunteers
ID00000406
Effects of Strength Training on Knee Osteoarthritis (OA)
Led by Indiana University · Updated on 2013-04-30
280
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
I
Indiana University
Lead Sponsor
N
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To understand the effects of leg strengthening exercise, we will study the effects of strength training of the legs in four groups of people: (1) osteoarthritis (OA) with knee pain; (2) OA without knee pain; (3) no OA but elderly with knee pain; and (4) normal elderly with no OA or knee pain. In each of the first three groups, we will look at whether people who do strength training have less pain and/or slower progression of x-ray signs of OA over 30 months than people who perform nonstrengthening, range-of-motion exercises. We are including the fourth group to find out whether people with OA (groups 1 \& 2) have the same response to strength training as healthy elderly people, and whether those with knee pain (groups 1 \& 3) have the same response to training as those without joint pain.
CONDITIONS
Official Title
Effects of Strength Training on Knee Osteoarthritis
Who Can Participate
Age: 60Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Males and females 60 to 100 years of age
You will not qualify if you...
- Knee joint replacement surgery
- Diabetes mellitus
- Uncontrollable hypertension
- Neuropathies of the lower extremity
- Poor mental cognition (i.e., inability to follow instructions)
Trial Site Locations
Total: 1 location
1
National Institute for Fitness and Sport
Indianapolis, Indiana, United States, 46202
Status Unknown
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
0
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