Actively Recruiting

Phase Not Applicable
Age: 16Years +
All Genders
NCT06261424

Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias

Led by Laval University · Updated on 2026-02-18

84

Participants Needed

5

Research Sites

160 weeks

Total Duration

On this page

Sponsors

L

Laval University

Lead Sponsor

M

McGill University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Spastic ataxias are a group of diseases causing symptoms such as walking difficulties and balance impairments that lead to a high risk of falls. No pharmacological treatments exist to treat these diseases. Unfortunately, little effort is made to develop non-pharmacological treatments specific to spastic ataxias despite the detrimental impact of the disease on several aspects of an individual's life and the high cost of falls for society each year. The three objectives of this project are: 1) to determine the effect of a 12-week rehabilitation program on disease severity as compared with usual care for individuals with spastic ataxias; 2) to identify which factors can help (or not) the implementation of the program in the clinical settings ("reel world"); and 3) to explore the cost-benefits of IMPACT \[rehabIlitation prograM for sPAstiC aTaxias\]. The team has developed the program to specifically target symptoms present in these patients and was previously pilot-tested. Based on the results obtained in this pilot project, positive effects are expected concerning the disease severity of participants. The investigators want, with this project, provide to health care professionals an option to offer better-suited services to people living with spastic ataxia worldwide.

CONDITIONS

Official Title

Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias

Who Can Participate

Age: 16Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a confirmed genetic diagnosis of ARSACS or SPG7
  • Be able to maintain standing position and to transfer
  • Be authorized by their treating neurologist
  • Speak French or English
  • Be able to give informed consent
Not Eligible

You will not qualify if you...

  • Currently participating in a rehabilitation program (self-reported)
  • Have another condition causing physical limitations
  • Feel uncomfortable in a swimming pool
  • Are pregnant

AI-Screening

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Trial Site Locations

Total: 5 locations

1

CIUSSS de la Capitale-Nationale, Hôpital de Baie-Saint-Paul

Baie-Saint-Paul, Quebec, Canada, G3Z 0K3

Not Yet Recruiting

2

CIUSSS de la Capitale-Nationale, Hôpital de La Malbaie

La Malbaie, Quebec, Canada, G5A 1T1

Not Yet Recruiting

3

CIUSSS du Centre-Sud-de-l'Île-de-Montréal, installation Centre de réadaptation Lucie-Bruneau

Montreal, Quebec, Canada, H2H 2N8

Actively Recruiting

4

CIUSSS de la Capitale-Nationale, installation IRDPQ

Québec, Quebec, Canada, G1M 2S8

Actively Recruiting

5

Clinique des maladies neuromusculaires du Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean, installation Hôpital Jonquière

Saguenay, Quebec, Canada, G7X 7X2

Actively Recruiting

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Research Team

E

Elise Duchesne, Ph D.

CONTACT

A

Andrée Hardy

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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