Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
FEMALE
NCT07271147

Effects of taVNS Combined With Dexmedetomidine on POVN

Led by Affiliated Hospital of Nantong University · Updated on 2025-12-09

176

Participants Needed

1

Research Sites

55 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To explore the effects and possible mechanisms of dexmedetomidine combined with taVNS on the incidence of postoperative nausea and vomiting in female patients undergoing laparoscopic surgery

CONDITIONS

Official Title

Effects of taVNS Combined With Dexmedetomidine on POVN

Who Can Participate

Age: 18Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 18 to 65
  • Undergoing elective laparoscopic surgery with general anesthesia
  • Classified as American Society of Anesthesiologists (ASA) physical status I to II
  • Able to understand study procedures and communicate with researchers
  • Willing to participate and provide written informed consent
Not Eligible

You will not qualify if you...

  • ASA anesthesia classification of III or higher
  • Poorly controlled hypertension, second degree or higher atrioventricular block, or obesity (BMI > 30 kg/m2)
  • Pregnant or breastfeeding
  • Allergic to study drugs, history of traumatic brain injury or gastrointestinal surgery
  • Liver or kidney dysfunction, alcoholism or drug abuse, mental illness
  • Use of antiemetics, opioids, psychoactive drugs, or corticosteroids within 24 hours before surgery
  • Presence of implanted stimulators, cochlear implants, or metal implants (except dental)
  • Skin lesions or dermatological diseases at stimulation site
  • Preoperative heart rate below 50 bpm or sinoatrial node disease
  • Unable to cooperate with assessments
  • Participation in other clinical trials

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Affiliated hospital of Nantong University

Nantong, Jiangsu, China, 226001

Actively Recruiting

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Research Team

C

Chao-Chao Zhong, M.D.;P.h.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Effects of taVNS Combined With Dexmedetomidine on POVN | DecenTrialz