Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
All Genders
Healthy Volunteers
NCT07141979

Effects of tDCS on Cognitive Flexibility and EEG Oscillations in Orthorexia Nervosa

Led by Istanbul Medipol University Hospital · Updated on 2026-04-01

48

Participants Needed

1

Research Sites

86 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Orthorexia Nervosa (ON); is a condition characterized by individuals being overly focused on healthy eating habits, constantly checking and classifying the foods they will consume. ON has not yet been clinically defined as an eating disorder or in a different category, and has not been included in DSM-5. Cognitive flexibility can be defined as a person's ability to quickly change their thinking and behaviors to adapt to different situations and changing conditions. It has been reported that cognitive flexibility skills are impaired in ON. There is evidence that tDCS, a neuromodulation method, increases cognitive flexibility skills. On the other hand, although there are EEG studies on eating disorders, there is no EEG study directly studying ON, and there is no information on the EEG profiles of individuals with high ON scores. For this reason, EEG studies on eating disorders and obsessive behaviors are generally generalized to orthorexia nervosa and are interpreted. This study aims to compare the EEG oscillations and cognitive flexibility skills of individuals with high ON scores with a control group and to examine the effects of anodal tDCS application on these two variables. For this purpose, a total of 48 individuals, 24 healthy and 24 high ON scores, will be included in the study. Participants will be randomly assigned to tDCS experimental and control groups. Therefore, 48 participants will be divided into 4 different subgroups of 12 people each. Data collection tools will be Informed Consent Form, Demographic Information Form, Beck Depression Inventory, Orthorexia Nervosa Test (TON-17), Cognitive flexibility task. First, participants will be subjected to a cognitive flexibility task by taking simultaneous EEG recordings, then tDCS stimulation will be initiated (active or sham) and after stimulation, a cognitive flexibility task will be performed by taking simultaneous EEG recordings again. EEG analyses will be performed using the Brain-Vision Analyzer program. Repeated Measures Analysis of Variance (within-group and between-groups) will be used in statistical analyses.

CONDITIONS

Official Title

Effects of tDCS on Cognitive Flexibility and EEG Oscillations in Orthorexia Nervosa

Who Can Participate

Age: 18Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 18 and 40 years old
  • Have a Beck Depression Inventory score of 17 or less
  • Have a Test for Orthorexia Nervosa (TON-17) score of 61 or more for the orthorexia group
Not Eligible

You will not qualify if you...

  • History of serious neurological or psychiatric illness
  • Currently taking medication that alters cortical excitability
  • Have visual defects that cannot be corrected with glasses
  • Use of intracranial metal objects, implanted stimulating devices, or pacemakers

AI-Screening

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Trial Site Locations

Total: 1 location

1

Istanbul Medipol University

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

S

Saliha Şahintürk Şentürk, PhD

CONTACT

M

Melek Özden, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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