Actively Recruiting

Age: 18Years - 90Years
All Genders
NCT05964712

Effects of Therapies in the Acromegaly Disease: Acral Morpho-functional Study

Led by Istituto Auxologico Italiano · Updated on 2025-08-03

30

Participants Needed

1

Research Sites

341 weeks

Total Duration

On this page

Sponsors

I

Istituto Auxologico Italiano

Lead Sponsor

P

Politecnico di Milano

Collaborating Sponsor

AI-Summary

What this Trial Is About

Acromegaly is a rare chronic disease due to excessive secretion of growth hormone (GH) and insulin-like growth factor-I (IGF-I), caused in over 98% of cases by GH-secreting pituitary adenoma. Prolonged exposure to GH/IGF-I excess is the cause of increased mortality and morbidity in these patients. Arthropathy occurs in about 75% of acromegalic patients. Any joint may be affected, with the development of osteoarthritis, arthralgia, and an increase in fracture risk. The aims of the present project are to evaluate the dimensions of hands and feet with the 3D scanner method and to perform a quantitative analysis of movement through Gait Analysis technique in de novo patients with acromegaly (group # 1) and in patients with different disease status (group #2).

CONDITIONS

Official Title

Effects of Therapies in the Acromegaly Disease: Acral Morpho-functional Study

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • De novo patients with acromegaly diagnosed according to Endocrine Society guidelines
  • Age 18 years or older
  • Acromegalic patients with different disease status
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Cardiorespiratory, neurological, or musculoskeletal disorder
  • Previous orthopedic surgery
  • Previous lower limbs traumatic injuries

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Istituto Auxologico Italiano IRCCS San Luca

Milan, Italy, 20149

Actively Recruiting

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Research Team

S

Sara Farina, Doctor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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