Study of Transversalis Fascia Plane Block to Reduce Opioid Use After Hand-Assisted Laparoscopic Kidney Donation Surgery

What this Trial Is About

Researchers are evaluating whether the transversalis fascia plane block TFPB, a regional anesthesia technique, can improve pain control after hand-assisted laparoscopic donor nephrectomy HALDN, a minimally invasive surgery for living kidney donors. The study aims to see if adding TFPB reduces opioid pain medication use and improves pain relief during the first 24 hours after surgery. This prospective, randomized controlled trial involves adult living kidney donors aged 18 to 80 approved for HALDN. Participants will be randomly assigned to one of two groups. One group will receive standard general anesthesia alone, while the other will receive general anesthesia plus an ultrasound-guided TFPB using 30 mL of 0.25% bupivacaine injected into the lower abdominal wall. All patients will receive standard postoperative pain treatment including paracetamol and patient-controlled morphine. Pain scores and opioid-related side effects will be monitored for 24 hours after surgery. During the study, patients will be assessed for opioid consumption within 24 hours, pain scores using the Numeric Rating Scale every 6 hours, and opioid side effects like nausea or itching. Patient satisfaction with pain control will also be recorded. The trial includes close monitoring of medication use and adverse events to compare pain management effectiveness between groups. Participation involves surgery, anesthesia, postoperative care, and follow-up assessments during the first day after surgery.

The Effects of Transversalis Fascia Plane Block on Opioid Consumption in Patients Undergoing Hand-Assisted Laparoscopic Donor Nephrectomy: A Randomized Controlled Prospective Study