Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06186869

Effects of Two Different Exercise Programs and Diet in Obese Subjects With NAFLD

Led by Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis · Updated on 2026-03-27

90

Participants Needed

1

Research Sites

168 weeks

Total Duration

On this page

Sponsors

A

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis

Lead Sponsor

A

Antonella Bianco

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of the study is to estimate the effectiveness of two different exercise programs combined with the Mediterranean diet versus diet alone on inflammatory status in subjects aged 18-65 years with obesity (BMI\>30) and Non-Alcoholic Fatty Liver Disease (NAFLD) (CAP \>248 dB/m).

CONDITIONS

Official Title

Effects of Two Different Exercise Programs and Diet in Obese Subjects With NAFLD

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • BMI 2 30 kg/m2 or abdominal circumference > 94 cm in men or > 80 cm in women
  • Aged 18 to 65 years, any gender
  • Diagnosis of hepatic steatosis confirmed by Fibroscan with CAP > 238 dB/m
Not Eligible

You will not qualify if you...

  • Normal weight or underweight individuals
  • Presence of diseases influencing steatosis other than those in inclusion criteria, including neurological, psychiatric, gastrointestinal, oncological, or cardiovascular diseases
  • Pregnancy or breastfeeding
  • Osteoarticular conditions preventing regular exercise
  • Inability to measure NAFLD degree by Fibroscan
  • Lack of medical certificate for non-competitive physical activity

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS De Bellis

Castellana Grotte, Bari, Italy, 70013

Actively Recruiting

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Research Team

E

Endrit Shahini, MD

CONTACT

A

Antonella Bianco

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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