Actively Recruiting

Phase Not Applicable
Age: 18Days +
All Genders
ID07070843

Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients

Led by Istanbul Saglik Bilimleri University · Updated on 2026-01-29

156

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to compare different methods of eye care in intensive care patients who are receiving mechanical ventilation. The study is designed as a prospective, randomized controlled experiment to evaluate how various eye care approaches affect the prevention of eye complications like conjunctival edema, eye infections, and dry eye. The trial includes patients with a Glasgow Coma Scale score below 12 who have been in the ICU for at least 24 hours, focusing on improving eye health during critical care. Participants will be randomly assigned to one of four groups: standard eye care using sterile gauze and saline; eye care using a specially developed eye care kit applied four times daily; eye care following a detailed eye care protocol with daily risk assessments and physician alerts; or a combination of the eye care kit and the protocol together. Nursing staff will be trained on the protocol and kit use, and eye coverage will be provided for patients with incomplete eyelid closure. The Schirmer test will be used to assess tear production before and after the interventions on days 1, 5, 7, and 10. During the study, patients will undergo daily eye assessments for signs of infection, conjunctival edema, and dry eye symptoms. Data collection will include clinical observations, Schirmer test results, and monitoring of eye care administration. The study will last for ten days starting 24 hours after ICU admission, with continuous documentation of eye care and ocular condition changes. Researchers will analyze the data to determine which eye care approach best prevents complications in ventilated ICU patients.

CONDITIONS

Brief Title

Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients

Who Can Participate

Age: 18Days +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Receiving mechanical ventilation
  • Glasgow Coma Scale (GCS) score less than 12
  • At least 24 hours have passed since ICU admission
  • Baseline Schirmer test result showing tear production greater than 5 mm before the study
Not Eligible

You will not qualify if you...

  • Diagnosed with brain death
  • Presence of facial or ocular trauma
  • Patients with head trauma
  • Patients who have undergone brain surgery
  • Patients diagnosed with an eye infection or chemosis
  • Patient death during the study period
  • Extubation before completion of the care period during the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Eye Care Intervention Period

Duration - 10 days

Participants receive different eye care practices assigned randomly to prevent eye complications while on mechanical ventilation in the intensive care unit. Eye care is performed according to the assigned group protocols, including standard eye care, use of an eye care kit, an eye care protocol, or a combination of both. Daily assessments for ocular risk factors, signs of infection, and conjunctival edema are performed. The Schirmer test is administered on days 1, 5, 7, and 10 to evaluate dry eye.

Daily visits with eye care provided 4 times daily; Schirmer tests on days 1, 5, 7, and 10

Trial Site Locations

Total: 1 location

1

University of Health Sciences (Sağlık Bilimleri Üniversitesi)

Istanbul, Istanbul, Turkey (Türkiye), 34668

Actively Recruiting

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Research Team

Y

Yildiz Deniz

B

Besey Oren

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

4

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