Actively Recruiting
Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients
Led by Istanbul Saglik Bilimleri University · Updated on 2026-01-29
156
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare different methods of eye care in intensive care patients who are receiving mechanical ventilation. The study is designed as a prospective, randomized controlled experiment to evaluate how various eye care approaches affect the prevention of eye complications like conjunctival edema, eye infections, and dry eye. The trial includes patients with a Glasgow Coma Scale score below 12 who have been in the ICU for at least 24 hours, focusing on improving eye health during critical care. Participants will be randomly assigned to one of four groups: standard eye care using sterile gauze and saline; eye care using a specially developed eye care kit applied four times daily; eye care following a detailed eye care protocol with daily risk assessments and physician alerts; or a combination of the eye care kit and the protocol together. Nursing staff will be trained on the protocol and kit use, and eye coverage will be provided for patients with incomplete eyelid closure. The Schirmer test will be used to assess tear production before and after the interventions on days 1, 5, 7, and 10. During the study, patients will undergo daily eye assessments for signs of infection, conjunctival edema, and dry eye symptoms. Data collection will include clinical observations, Schirmer test results, and monitoring of eye care administration. The study will last for ten days starting 24 hours after ICU admission, with continuous documentation of eye care and ocular condition changes. Researchers will analyze the data to determine which eye care approach best prevents complications in ventilated ICU patients.
CONDITIONS
Brief Title
Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Receiving mechanical ventilation
- Glasgow Coma Scale (GCS) score less than 12
- At least 24 hours have passed since ICU admission
- Baseline Schirmer test result showing tear production greater than 5 mm before the study
You will not qualify if you...
- Diagnosed with brain death
- Presence of facial or ocular trauma
- Patients with head trauma
- Patients who have undergone brain surgery
- Patients diagnosed with an eye infection or chemosis
- Patient death during the study period
- Extubation before completion of the care period during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Duration - 10 days
Participants receive different eye care practices assigned randomly to prevent eye complications while on mechanical ventilation in the intensive care unit. Eye care is performed according to the assigned group protocols, including standard eye care, use of an eye care kit, an eye care protocol, or a combination of both. Daily assessments for ocular risk factors, signs of infection, and conjunctival edema are performed. The Schirmer test is administered on days 1, 5, 7, and 10 to evaluate dry eye.
Daily visits with eye care provided 4 times daily; Schirmer tests on days 1, 5, 7, and 10
Trial Site Locations
Total: 1 location
1
University of Health Sciences (Sağlık Bilimleri Üniversitesi)
Istanbul, Istanbul, Turkey (Türkiye), 34668
Actively Recruiting
Research Team
Y
Yildiz Deniz
B
Besey Oren
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
4
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here