Actively Recruiting

Phase Not Applicable
Age: 25Years +
All Genders
NCT06853288

Effects of Ultra Processed Food on Intestinal Energy Harvest

Led by Columbia University · Updated on 2025-10-03

20

Participants Needed

1

Research Sites

87 weeks

Total Duration

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Sponsors

C

Columbia University

Lead Sponsor

U

UNC Gillings School of Global Public Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human body; this is done by measuring how many calories are in the stool. The investigators propose to test a very high ultra-processed food diet where 80% of calories are coming from ultra processed food and a low ultra processed food diet where 20% of the calories are coming from ultra processed food. This study will compare stool sample energy content of the two diets.

CONDITIONS

Official Title

Effects of Ultra Processed Food on Intestinal Energy Harvest

Who Can Participate

Age: 25Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • BMI 30-40kg/m2
  • Weight stable
  • Able to download app and willing to use it for duration of study
  • Does own grocery shopping
  • Otherwise healthy
Not Eligible

You will not qualify if you...

  • Pregnancy
  • History of or planned bariatric surgery
  • History of anti obesity medications

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Columbia University Irving Medical Center

New York, New York, United States, 10032

Actively Recruiting

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Research Team

F

Faris M Zuraikat, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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