Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT04824053

Effects of UNICLA-A2 Dairy Products on Patients at High-risk of Colorectal Cancer Development

Led by Instituto de Investigación Sanitaria Aragón · Updated on 2026-05-12

34

Participants Needed

1

Research Sites

354 weeks

Total Duration

On this page

Sponsors

I

Instituto de Investigación Sanitaria Aragón

Lead Sponsor

C

Cooperativas Lacteas Unidas

Collaborating Sponsor

AI-Summary

What this Trial Is About

Dietary intervention with UNICLA-A2 milk products containing beta casein A2 protein, and higher levels of omega-3 fatty acids and selenium may contribute to maintain the intestinal integrity, reduce inflammatory processes, normalize the immune system, protect against oxidative damage and equilibrate the gut microbiota in high-risk colorectal cancer patients who have undergone polypectomy

CONDITIONS

Official Title

Effects of UNICLA-A2 Dairy Products on Patients at High-risk of Colorectal Cancer Development

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with high-risk colorectal polyps or related conditions including: at least 10 adenomas, at least 5 proximal serrated polyps, at least 2 serrated polyps ≥10 mm, Serrated Polyposis Syndrome, early invasive colorectal cancer stage pT1 resected endoscopically, sessile or flat lesion ≥20 mm with fragmented resection, previous polyp resection with unassessable margin, or intramucosal carcinoma in situ (pTis)
  • Regular consumer of milk and dairy products
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • History of allergic reaction to compounds similar to the study products
  • Incomplete or poor quality colonoscopy (Boston score <6)
  • Regular or predictable use of acetylsalicylic acid, NSAIDs, misoprostol, corticosteroids, or statins during the study
  • Previous gastrointestinal surgery affecting nutrient absorption
  • History of familial adenomatous polyposis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Angel Lanas Arbeloa

Zaragoza, Zaragoza, Spain, 50009

Actively Recruiting

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Research Team

A

Angel Lanas Arbeloa, MD, PhD

CONTACT

P

Pilar Irun, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Effects of UNICLA-A2 Dairy Products on Patients at High-risk of Colorectal Cancer Development | DecenTrialz