Actively Recruiting
The Effect of Upper Extremity Low-Volume High-Intensity Interval Training on Physical and Cognitive Functions in Heart Failure Patients
Led by Tarsus University · Updated on 2025-01-03
30
Participants Needed
2
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of upper extremity low-volume high-intensity interval training (LV-HIIT) on physical and cognitive functions in patients with heart failure with preserved ejection fraction (HFpEF). This randomized controlled trial includes patients who are clinically stable with HFpEF to understand how this specific exercise impacts their physical capacity and cognitive abilities. The study aims to compare the intervention group receiving LV-HIIT with a control group receiving standard medical treatment. Participants in the intervention group will undergo an 8-week training program using an arm ergometer. This program includes 4 minutes of warm-up and cool-down at 50% of maximum workload (Wmax), 1 minute of high-intensity training at 85-95% Wmax, and 6 intervals of active recovery at 50-70% Wmax twice weekly. The control group will continue with their usual medical care without additional training. During the study, participants will be assessed before and after the 8-week period for various physical and cognitive outcomes. These include maximal arm exercise capacity, functional capacity, upper extremity muscle strength, reaction time, cognitive function, postural sway, and heart rate variability. Secondary measures such as hand steadiness, anxiety and depression, and daily living activities will also be evaluated. The research involves regular monitoring and functional tests to track changes and safety throughout the trial.
CONDITIONS
Brief Title
Effects of Upper Extremity Low Volume HIIT in Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical condition stable for at least 4 weeks
- New York Heart Association functional classification I-II to III
- Age 18 years or older
You will not qualify if you...
- History of coronary artery bypass graft (CABG) surgery
- Unstable angina pectoris
- Severe arrhythmia
- Acute pericarditis, endocarditis, or myocarditis
- Severe left ventricular failure (ejection fraction less than 40%)
- Acute pulmonary embolism
- History of syncope
- Dissecting aneurysm
- Thrombophlebitis
- Orthopedic disorders that may interfere with exercise
- Uncontrolled hypertension or severe pulmonary arterial hypertension
- Moderate to severe valve disease
- Decompensated congestive heart failure
- Electrolyte abnormalities
- Hypertrophic cardiomyopathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 8 weeks
Participants in the intervention group perform low-volume, high-intensity interval training using an arm ergometer two days per week for a total of eight weeks. Participants in the control group continue with standard medical treatment.
Twice weekly visits for training or follow-up
Trial Site Locations
Total: 2 locations
1
Tarsus University, TARSUS, Mersin
Mersin, Mersin, Turkey (Türkiye)
Actively Recruiting
2
Nurel Ertürk, TARSUS, Mersin
Yenişehir, Mersin, Turkey (Türkiye)
Actively Recruiting
Research Team
N
Nurel ERTÜRK
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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