Actively Recruiting
The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks
Led by Ziekenhuis Oost-Limburg · Updated on 2026-03-24
174
Participants Needed
1
Research Sites
123 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Peripheral nerve blocks are essential in ensuring effective regional anesthesia and postoperative analgesia in forefoot surgery for hallux valgus repair, with or without minor concomitant toe procedures. Many factors influence the onset and duration of peripheral nerve blocks. In the advent of ultrasound-guided nerve blocks, the accuracy in administering LA has significantly improved, potentially reducing the required dosage, which is also associated with less risk for toxicity. However, the effect of the concentration of LA on the onset time and duration of ultrasound-guided ankle blocks for forefoot surgery has not yet been studied. This poses a clinically relevant dilemma regarding the necessity of administering lower or higher concentrations of ropivacaine to achieve a clinically relevant faster onset time and longer duration of an ankle block.
CONDITIONS
Official Title
The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provide signed and dated informed consent
- Age 18 up to and including 75 years, scheduled for elective forefoot surgery for hallux valgus repair, with or without minor toe procedures, osteotomies, arthrodesis, or toe extensor/flexor procedures, under unilateral ankle block
- ASA physical status I, II, or III
- Able to walk independently, with or without assistive devices
- Able to learn and perform sensory and motor assessments at home after surgery
You will not qualify if you...
- Language barrier
- Preexisting lower extremity neuropathy
- Contraindications to ankle block such as local infection, edema, burn, soft tissue trauma, or scarring near the block site
- Contraindications for NSAIDs use
- Allergy to local anesthetics
- Uncontrolled anxiety, psychiatric, or neurological disorders that may affect assessments
- Weight below 50 kg due to dosing limits
- Use of opioids or gabapentin less than 3 days before surgery
- Contraindications for paracetamol use
- Contraindications for tramadol use
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Ziekenhuis Oost-Limburg
Genk, Limburg, Belgium, 3600
Actively Recruiting
Research Team
I
Imré Van Herreweghe, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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