Actively Recruiting
Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial
Led by University of Minnesota · Updated on 2025-09-22
216
Participants Needed
3
Research Sites
181 weeks
Total Duration
On this page
Sponsors
U
University of Minnesota
Lead Sponsor
N
Northwestern University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this randomized crossover trial is to compare the differences in psychological and physiological effects of walking in two different outdoor environments (urban/suburban commercial environments vs. urban/suburban nature areas/preserves) in adults with prediabetes. The main questions it aims to answer are: * Do psychological measures of stress, anxiety, and affect improve more in one type of outdoor environment over the other? * Do physiological measures of stress improve more in one type of outdoor environment over the other? As this is a crossover trial, participants will serve as their own controls. Researchers will compare both the psychological and physiological effects walking in the two types of outdoor environments. Participants will: * Walk 150-minutes per week for six weeks in each of the two outdoor conditions. * Visit the clinic four times, including before and after each six-week walking period. * Collect saliva samples immediately proceeding or following the four clinic visits. * Return to their pre-study level of physical activity for a 5-week washout period between each of the two walking interventions.
CONDITIONS
Official Title
Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 25 and 64 years
- Overweight or obese with BMI between 20.0 and 39.9 kg/m2 by self-report and 20.0 to 41.9 kg/m2 by measurement
- Documented prediabetes diagnosis within one year based on lab tests or study screening HbA1c in the range 5.7% to 6.49%
- Currently exercising 100 minutes or less per week of moderate to vigorous activity
- No exercise contraindications as assessed by the Physical Activity Readiness Questionnaire (PAR-Q), or have a doctor's note confirming safety
- Stable weight over the last 3 months with less than 10% change
- Not currently pregnant, planning pregnancy, or breastfeeding
- Willing to maintain current diet and exercise habits except study exercise protocol
- Own a smartphone and willing to download the Garmin Connect app
- Able to speak and understand English
- Any income level
- Any race or ethnicity
You will not qualify if you...
- Younger than 25 or older than 64 years
- BMI less than 20 or greater than or equal to 42
- HbA1c level less than 5.7% or greater than 6.4%
- Currently exercising more than 100 minutes per week
- Contraindications to exercise per PAR-Q
- Physical or mental disability preventing adherence to the intervention
- Past or current diabetes diagnosis or use of diabetic medications
- History of cardiovascular disease events such as heart attack, ablation, pacemaker, or stroke
- Current cancer or heart disease treatment (lipid and hypertension medications allowed but tracked)
- Recent or anticipated medication changes affecting study outcomes
- Use of medications significantly interfering with autonomic nervous system
- Current tobacco or nicotine use or quit within last six months
- Excessive alcohol or recreational drug use
- Unstable weight over last 3 months (more than 10% change)
- Major surgery planned or recent bariatric surgery within 2 years
- Within one year postpartum, currently pregnant, or planning pregnancy during study
- Currently breastfeeding
- Unwilling to comply with study randomization or maintain diet and exercise habits
- Participation in another interventional clinical trial
- Previous participation in this study
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Lake Forest Hospital
Lake Forest, Illinois, United States, 60045
Actively Recruiting
2
Central DuPage Hospital
Winfield, Illinois, United States, 60190
Actively Recruiting
3
Epidemiological Clinical Research Center
Minneapolis, Minnesota, United States, 55415
Actively Recruiting
Research Team
S
Sarah Rydell, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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