Actively Recruiting

Phase Not Applicable
Age: 40Years - 80Years
All Genders
NCT07006883

Effects of a Yoga Program on the Functionality of Individuals

Led by University of Nove de Julho · Updated on 2025-12-18

90

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

There is a notable and emerging use of structured exercise programs incorporating Yoga for chronic musculoskeletal pain. However, regarding knee osteoarthritis (KOA), the effectiveness of Yoga remains uncertain to justify its inclusion in therapeutic exercise programs in routine clinical practice. Therefore, the aim of this project is to evaluate the effects of Yoga on functionality in individuals with KOA. For this purpose, participants with KOA, including individuals of both sexes, aged 45 years or older, with a clinical diagnosis of KOA, will be randomly allocated using a random sequence generated by software, organized in six blocks of 24 codes, with an allocation ratio of 1:1, numbered sequentially from 1 to 126. Allocation will be concealed and performed after pre-intervention assessment and confirmation of eligibility criteria. Participants will be distributed into two groups: (1) Experimental group - Yoga (n = 45) and (2) Control group - therapeutic exercise (n = 45). The intervention will last 8 weeks, with assessments conducted at baseline, after 4 weeks, and after 8 weeks of the intervention programs. The following outcome measures will be used: Knee Injury and Osteoarthritis Outcome Score (KOOS), Berg Balance Scale (BBS), Numeric Pain Rating Scale (NPRS), Pain Self-Efficacy Questionnaire (PSEQ), Global Perceived Effect Scale (GPE), 30-Second Sit-to-Stand Test (30s-STS), Timed Up and Go Test (TUG), and Maximal Voluntary Isometric Contraction (MVIC). Data analysis will include a normality test to verify the distribution of the data, followed by the appropriate statistical tests for intra- and intergroup comparisons. The comparisons will consider two factors: time and group. A significance level of 5% (p \< 0.05) will be adopted for all analyses.

CONDITIONS

Official Title

Effects of a Yoga Program on the Functionality of Individuals

Who Can Participate

Age: 40Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • A clinical diagnosis of knee osteoarthritis with knee pain for more than 3 months
  • Morning stiffness less than 30 minutes
  • Presence of crepitus
  • Bone tenderness and no palpable heat
  • Diagnosis confirmed radiographically with Kellgren and Lawrence grade 1 to 3
  • Aged between 45 and 80 years
Not Eligible

You will not qualify if you...

  • Bilateral hip or knee osteoarthritis
  • Severe osteoporosis
  • Fibromyalgia
  • History of tumors or cancer
  • Active inflammatory joint diseases such as rheumatoid arthritis or gout
  • Undergoing any joint replacement of the lower extremity
  • Neurological diseases including Parkinson's disease, stroke, multiple sclerosis, muscular dystrophies, neuromotor disease, or Alzheimer's disease
  • Infected wounds or osteomyelitis in the knee region
  • Deep vein thrombosis or thrombophlebitis
  • Sensory changes in the lower limbs
  • Cognitive or cardiopulmonary impairments limiting exercise performance
  • Use of walking assistance devices
  • Recent trauma to the knee
  • Current or prior treatment involving physiotherapy, intra-articular corticosteroids, anti-inflammatories, opioid medication, or chondroprotective within 6 months before the study start

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Nove de Julho

São Paulo, Brazil, 01504-001

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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