Actively Recruiting
Efficacy and Accuracy of Combined Localization Versus Single Localization in Non-palpable Breast Cancer
Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2024-07-03
170
Participants Needed
1
Research Sites
145 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The standard method for localizing non-palpable breast cancer is currently preoperative wire-guided localization, its positive margin rate still remains around 20-50%. This study aims to compare the accuracy and efficacy of wire vs. combined breast tissue markers in localizing non-palpable breast cancer.
CONDITIONS
Official Title
Efficacy and Accuracy of Combined Localization Versus Single Localization in Non-palpable Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 18 years or older
- Eastern Cooperative Oncology Group score of 2 or higher
- Pathologically diagnosed untreated breast cancer by core-needle biopsy
- Histologically confirmed non-palpable in situ or invasive breast cancer requiring localization
- Willingness to undergo breast-conserving surgery with no contraindications
You will not qualify if you...
- Inflammatory breast cancer or Paget's disease
- Breast deformities or conditions affecting breast conservation success
- Contraindications to breast-conserving surgery or systemic diseases, mental disorders, or conditions affecting trial participation
- Severe bleeding or coagulation disorders
- Pregnancy or lactation
- Prior use of hookwire, radioactive 125I seed, or other localization techniques in breast lesions
- Stage IV disease or unresectable breast lesions
- Other diseases affecting survival
- Multicentric breast cancer or lesions larger than 5 cm on imaging
- Previous radical mastectomy for ipsilateral breast cancer or chest wall radiotherapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guangzhou, Guangdong, China, 510120
Actively Recruiting
Research Team
C
Chang Gong, doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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