Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07056049

The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery

Led by Adi Negev-Nahalat Eran · Updated on 2025-07-17

50

Participants Needed

2

Research Sites

104 weeks

Total Duration

On this page

Sponsors

A

Adi Negev-Nahalat Eran

Lead Sponsor

B

Ben-Gurion University of the Negev

Collaborating Sponsor

AI-Summary

What this Trial Is About

Intervention abstract Background: Stroke is the leading cause of long-term disability, and the second leading cause of death in the western world. Most stroke survivors will suffer from motor and cognitive disturbances for the rest of their life, which negatively affects their normal daily life. Despite the decline in stroke-related mortality over the past decades, the outcome of rehabilitation programs does not improve, and is predictable regardless of the program used. Still, several human and animal studies show that high capacity of training in the early stages post stroke improve motor recovery. This notion is far from being well established. Aim: Studying the effect of high-dosage, high-intensity training program in the subacute period on upper extremity motor recovery. Population: Stroke survivors. Study duration: 6 months. Study protocol: Participants will receive additional technology-based upper extremity training for 120 min/day, 5d/w, 4 weeks. They will be monitored pre and post training, and 6 months post-stroke. Outcome measures will include clinical, kinematic and adherence measures (see complete list in the protocol).

CONDITIONS

Official Title

The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Ischemic or hemorrhagic stroke (hemispheric or brainstem) confirmed by CT or MRI
  • First-ever stroke or previous stroke without upper extremity weakness
  • Time after stroke onset between 1 week and 6 weeks
  • Active shoulder flexion of at least 20 degrees and partial wrist and/or finger active movement
  • Ability to provide informed consent
Not Eligible

You will not qualify if you...

  • Painful shoulder that limits active forward reach
  • Severe spasticity or non-neural loss of range of motion
  • Cognitive or communication impairments as determined by the clinical team
  • Unstable medical conditions

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Adi Negev-Nahalat Eran

Ofakim, Israel

Not Yet Recruiting

2

Adi Negev-Nahalat Eran

Ofakim, Israel

Actively Recruiting

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Research Team

G

Gil Meir

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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