Actively Recruiting
Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease
Led by Elsan · Updated on 2026-04-23
172
Participants Needed
2
Research Sites
391 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dupuytren's disease is a frequent hereditary disease in Northern Europe. It is a degenerative disease affecting the palmar aponeurosis of the hand. It develops a progressive contractile fibrosis which cuts the hypodermic fatty tissue, adheres to the skin and the phalanges, gradually bending the affected rays, resulting in significant functional impotence. Various medical and surgical treatments are available.
CONDITIONS
Official Title
Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Dupuytren's disease at Tubiana stage II-IV on one or more fingers, not previously operated
- Surgery recommended by aponeurectomy
- Skin pinch on the back of the arm more than 1 cm
- Affiliated with a social security system
- Provided informed consent to participate
You will not qualify if you...
- Previous surgery for Dupuytren's disease
- Disease affecting only the thumb
- Need for total skin graft or pedicle flap on all treated fingers
- Active autoimmune disease
- Previous treatment with collagenase
- Pregnant or breastfeeding women
- Under legal protection
- Contraindications to MRI (only for patients at the coordinating center)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Institut Aquitain de la Main
Pessac, France, 33600
Actively Recruiting
2
Santé Atlantique ELSAN
Saint-Herblain, France, 44800
Actively Recruiting
Research Team
E
Elias SAWAYA, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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