+1 877 705 1914• 24 / 7
HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
All Genders
ID07488598

Behavioral Therapy to Treat Chronic Refractory Cough in Adults with Laryngeal Hyperresponsiveness

Led by Assiut University · Updated on 2026-04-23

30

Participants Needed

1

Research Sites

10 weeks

Total Duration

AI-Summary

What this Trial Is About

Chronic cough lasting more than eight weeks is a common problem that greatly affects physical, psychological, and social quality of life. Despite treatment of common causes like asthma and gastroesophageal reflux disease, many patients continue to experience persistent symptoms classified under cough hypersensitivity syndrome. This condition is linked to laryngeal hyperresponsiveness, which causes symptoms such as throat irritation, voice changes, frequent throat clearing, and cough triggered by talking or exposure to irritants. The study evaluates behavioral therapy as a non-drug approach for chronic cough in patients with laryngeal hyperresponsiveness. Behavioral therapy involves patient education, cough suppression techniques, breathing retraining, vocal hygiene counseling, and strategies to reduce throat irritation and improve control over the urge to cough. About 30 patients with chronic refractory cough will receive this therapy to assess its effectiveness as a management strategy. Participants will be involved in treatment and monitored over six months to assess outcomes. Researchers will evaluate treatment effects on chronic cough using clinical features and patient responses. The study includes assessments of cough frequency, sensitivity, and quality-of-life impact related to cough. Safety and adherence will be monitored throughout the study, with a focus on improving symptoms related to laryngeal hyperresponsiveness.

CONDITIONS

Brief Title

Efficacy of Behavioral Therapy for Chronic Refractory Cough

Research Team

M

Mohamed Shaaban Mohamed Mahfouz, Resident

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here