Actively Recruiting

Phase 2
Age: 18Years +
FEMALE
NCT07492160

Efficacy of Cabergoline in Inhibiting Lactation and Alleviating Breast Symptoms

Led by Maimonides Medical Center · Updated on 2026-03-25

348

Participants Needed

1

Research Sites

106 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn whether cabergoline can prevent lactation and reduce breast symptoms in pregnant people aged 18 years or older undergoing abortion or pregnancy loss between 12 and 18 weeks of gestation. The main questions it aims to answer are: Does cabergoline decrease the proportion of participants who experience breast symptoms (including breast engorgement, milk leakage, tenderness, and need for pain relief) after abortion or pregnancy loss? Does cabergoline reduce the severity of breast symptoms and associated bother compared with placebo? Researchers will compare participants receiving cabergoline to those receiving placebo to determine whether cabergoline reduces the frequency and severity of breast symptoms following abortion or pregnancy loss. Participants will: Complete a baseline survey assessing breast symptoms prior to the abortion or pregnancy loss procedure Receive a single oral dose of either cabergoline (1 mg) or placebo approximately one hour after the procedure Complete follow-up surveys on days 2, 3, 4, 7, and 14 after the procedure to assess breast symptoms and related bother A subset of participants will provide blood samples at selected time points to measure serum prolactin levels

CONDITIONS

Official Title

Efficacy of Cabergoline in Inhibiting Lactation and Alleviating Breast Symptoms

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant people aged 18 years or older
  • Gestational age between 12 and 18 weeks
  • Undergoing treatment for spontaneous or induced abortion at Maimonides Medical Center
  • Able to provide informed consent
  • Willing and able to complete study surveys
Not Eligible

You will not qualify if you...

  • Prior mastectomy
  • Currently breastfeeding
  • Current use of a dopamine agonist or dopamine antagonist medication
  • Known contraindication to Cabergoline according to the medication prescribing information

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Maimonides Medical Center

Brooklyn, New York, United States, 11219

Actively Recruiting

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Research Team

J

June Ng, MD

CONTACT

O

Olivia Sher, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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