Actively Recruiting
Efficacy of Cashew Nut Protein Immunotherapy
Led by Medical University of Warsaw · Updated on 2025-01-30
39
Participants Needed
1
Research Sites
159 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
It is a randomized, single-center, controlled trial to evaluate the effectiveness of oral immunotherapy with cashew protein compared with standard treatment (elimination diet) in pediatric patients with cashew allergy.
CONDITIONS
Official Title
Efficacy of Cashew Nut Protein Immunotherapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 4 and 17 years
- Confirmed IgE-mediated cashew allergy with positive skin prick test or specific IgE level >0.35 kUA/l
- Allergic reaction to cashew protein during oral food challenge
- Signed informed consent by parent/legal guardian and patient if older than 16 years
- Cooperation by patient and caregivers with the research team
You will not qualify if you...
- No confirmed allergy to cashew
- Negative provocation test with cashew
- Severe asthma or poorly controlled mild/moderate asthma (FEV1 <80%, FEV1/FVC <75%, or recent hospitalization for asthma)
- Receiving oral, sublingual, or subcutaneous immunotherapy to other allergens during the study
- Eosinophilic gastroenteritis
- Chronic diseases requiring ongoing treatment such as heart disease, epilepsy, metabolic diseases, diabetes
- Use of oral steroids for more than 1 month in the past year, or multiple steroid courses in the past year, or recent steroid use within 3 months
- Biological treatment
- Continuous need for antihistamines
- Therapy with beta-blockers, ACE inhibitors, or calcium channel blockers
- Pregnancy
- Lack of consent or cooperation with study requirements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical University of Warsaw
Warsaw, Masovian Voivodeship, Poland, 02-091
Actively Recruiting
Research Team
K
Katarzyna Grzela, PhD, MD
CONTACT
A
Agnieszka Szczukocka-Zych, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here