Testing Cerebello-spinal Direct Current Stimulation with Treadmill Training to Improve Walking in Adults Aged 18 to 75 With Chronic Stroke

What this Trial Is About

This research aims to evaluate whether cerebello-spinal direct current stimulation csDCS can improve walking ability and overall mobility in people who have chronic stroke-related gait disorders. The study also investigates the safety of this stimulation method by comparing its effects to a sham procedure, which mimics stimulation without actual impact. The trial is a phase 2 clinical study focused on stroke rehabilitation and functional mobility enhancement. Participants will receive either active csDCS or sham csDCS combined with treadmill training daily for two weeks. The csDCS device influences spinal pathways and reflex excitability to promote lasting neuroplastic changes. The sham procedure involves stopping the current after 30 seconds to create a sensation without neuromodulation. Both groups will undergo treadmill training alongside their assigned intervention. Participants will be assessed on their functional mobility before treatment, immediately after the two-week intervention, and again at a 30-day follow-up. Researchers will also measure independence level, lower limb motor function, balance, perceived changes from treatment, and spasticity at these same time points. The study uses a randomized, double-blind design to monitor outcomes and side effects during and after treatment, with total participation lasting about one month.

Efficacy of Cerebello-spinal Direct Current Stimulation (csDCS) on Functional Mobility in Chronic Stroke Patients