Actively Recruiting
Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth Randomized Clinical Trial
Led by Minia University · Updated on 2026-01-07
26
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of chitosan dressing in pulpotomy procedures for immature permanent teeth, which are young teeth with incomplete root formation. These teeth are vulnerable to decay and injury that can expose and damage the pulp, stopping root development and leaving the tooth fragile. Preserving pulp vitality is crucial to allow continued root growth. Pulpotomy, a common method to keep pulp healthy by removing infected tissue and covering the area with a biocompatible material, is recommended for managing pulp exposure in these teeth. This study compares two treatments for pulpotomy in immature permanent teeth affected by caries or trauma: one group receives a chitosan dressing applied to the pulp stump to control bleeding, while the other group receives cotton dampened with normal saline for hemostasis. Chitosan is a natural, non-toxic substance with antimicrobial and healing properties, and its effectiveness and safety in this dental procedure are being assessed. Participants will be randomly assigned to one of these two groups. Participants aged 7 to 15 with immature maxillary anterior teeth affected by caries or trauma will be involved. The study includes a follow-up period of up to 12 months, during which outcomes such as post-operative pain will be monitored. Researchers will evaluate the success of treatment through clinical assessments and patient reports over this time. The trial aims to provide evidence on the use of chitosan dressings to support healing and root development in immature permanent teeth.
CONDITIONS
Brief Title
Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with immature maxillary anterior teeth
- Patients with caries or traumatic exposed teeth
- Patients free from systemic disease affecting healing (class I ASA)
- Patients who agree to consent and commit to follow-up period
You will not qualify if you...
- Patients with mature roots
- Patients with systemic disease affecting healing
- Patients with signs of periapical inflammation
- Patients unable or unwilling to participate in 1-year follow-up
- Teeth with periodontal involvement
- Teeth with vertical root fractures
- Non-restorable teeth
- Cases with previously initiated endodontic treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility assessment
Duration - Single treatment visit
Participants undergo pulpotomy where a chitosan dressing or a cotton damped with normal saline is applied to the pulp stump for hemostasis in immature permanent teeth.
1 treatment visit (in-person)
Duration - 6 to 12 months
Participants are monitored for post-operative pain and treatment success during a follow-up period lasting up to 12 months.
Multiple follow-up visits over 6 to 12 months
Trial Site Locations
Total: 1 location
1
Minia University Hospital
Minya, Egypt
Actively Recruiting
Research Team
S
Salsabil Mohammed Naguib, MSc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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