Randomized Controlled Trial Comparing Fractional Erbium:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars

What this Trial Is About

This research aims to compare two treatments for atrophic acne scars on the face in adults between 18 and 30 years old. It evaluates whether the combined use of fractional Erbium:Glass and Thulium lasers results in better scar improvement than microneedling. Acne scars can impact self-esteem and quality of life, so finding more effective treatments is important for patients. The trial is a randomized controlled study sponsored by the University of Nove de Julho. Participants receive one of two treatments assigned by chance: microneedling with an electronic pen using a 12-needle cartridge at 2mm depth, or a combination of fractional Erbium:Glass laser focused on scarred areas followed immediately by fractional Thulium laser applied over the full face. Both groups undergo three treatment sessions spaced four weeks apart. The lasers deliver energy to promote skin remodeling, while microneedling stimulates repair through small skin punctures. Throughout the study, participants are assessed before treatment, and then at 30 days and up to 16 weeks after the last session. Independent evaluators use standardized photos and an acne scar grading scale to measure improvement. Patients also report their satisfaction, pain levels, and any side effects during follow-up visits up to 90 days after treatment. Quality of life and aesthetic improvement are also evaluated to understand overall treatment effects.

Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars