Combining Platelet-rich Plasma and Crystallized Phenol to Treat Pilonidal Sinus Disease in Children A Randomized Controlled Trial

What this Trial Is About

Researchers are evaluating the effectiveness of combining platelet-rich plasma PRP with crystallized phenol treatment for pilonidal sinus disease in children. Pilonidal sinus disease involves infections near the tailbone, and previous treatments have used phenol due to its antiseptic and anesthetic properties. This study aims to see if adding PRP after crystallized phenol can speed healing and improve outcomes in pediatric patients. Patients begin treatment with manual or laser hair removal to reduce hair in the affected area by over 90%. Those with abscesses receive incision, drainage, and antibiotics first. Under local anesthesia, the sinus area is cleaned and disinfected, hair and granulation tissue removed, and crystallized phenol is applied carefully to fill the cavity. In one group, PRP injections are also given around the wound during the same session to promote tissue healing. During the study, participants are monitored for healing progress, pain levels, cosmetic results, and recurrence of the sinus over several weeks. Researchers will assess the time to return to daily activities, healing time, and rates of complications such as bleeding, infection, and skin burns. Follow-up visits and evaluations continue for seven weeks to track treatment success and safety.

The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease