Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT04899466

Efficacy Evaluation of ActiGraft in Secondary Closure of Abdominal Surgical Wound Dehiscence

Led by RedDress Ltd. · Updated on 2024-11-15

20

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, single arm study, consisting of 20 women with abdominal surgical wound dehiscence that requires secondary closure. The participants will receive a weekly application of ActiGraft for 4 weeks, or until complete healing of the wound (the earlier of the two). An historic matched-control group of 20 patients will be compared retrospectively

CONDITIONS

Official Title

Efficacy Evaluation of ActiGraft in Secondary Closure of Abdominal Surgical Wound Dehiscence

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 18 years
  • Female patients who had a laparotomy within 3 weeks before joining the study
  • Presence of surgical wound dehiscence requiring secondary closure
  • Time since wound dehiscence between more than 24 hours and less than 6 days
  • Open wound involving epidermis, dermis, and subcutaneous fat
  • Ability to provide informed consent
Not Eligible

You will not qualify if you...

  • Presence of necrotizing fasciitis
  • Presence of fascial dehiscence
  • Unable to have blood drawn in the required amount (up to 18 mL per week)
  • Known coagulation disorders, abnormal platelet levels, or receiving intravenous heparin
  • Pregnancy
  • Current or planned use of systemic steroids (Prednisone more than 10 mg/day or equivalent) within the past 30 days

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Meir Medical Center

Kfar Saba, Israel

Actively Recruiting

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Research Team

S

Sharon Sirota

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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