Studying Hiatal Closure Surgery as a Treatment for Early Gastro-Esophageal Reflux Disease GERD in Adults 18 to 50

What this Trial Is About

Gastro-Esophageal Reflux Disease GERD affects millions of Americans, many of whom rely on long-term medication to manage symptoms. This research evaluates the effectiveness of hiatal closure surgery for early GERD, aiming to restore the function of the lower esophageal sphincter without the need for more extensive procedures like fundoplication. The study seeks to provide new insights using minimally invasive techniques to treat patients with small hiatal defects and symptomatic GERD. The study focuses on patients undergoing hiatal closure alone, a surgical approach that repairs the hiatal defect and aims to improve sphincter function. This method is being assessed using minimally invasive laparoscopic surgery. The research team will analyze outcomes to determine how well this treatment controls GERD symptoms and restores function, with procedures performed on suitable surgical candidates. Participants will have their pH levels tested at one and two years after surgery to measure treatment effectiveness. The study will monitor these patient-centered outcomes carefully over time to evaluate the recovery of esophageal function. The trial involves adult participants aged 18 to 50 who meet specific health criteria, and it is sponsored by the University of Chicago, with an estimated completion date in October 2028.

Efficacy Of Hiatal Closure For GERD