Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 65Years
All Genders
NCT06647901

Efficacy of ICG-based NIR Imaging in Intralesional Curettage of Giant Cell Tumors of Bone in Limbs: a Prospective, Single-center, Single-arm, Open Study

Led by Tang Xiaodong · Updated on 2024-10-18

45

Participants Needed

1

Research Sites

209 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

ICG fluorescence imaging will be applied during the intralesional curettage of giant cell tumor of bone in the limbs. This study aims to preliminarily explore whether ICG fluorescent-guided curettage could find small residual tumors and reduce the recurrence rate of tumor.

CONDITIONS

Official Title

Efficacy of ICG-based NIR Imaging in Intralesional Curettage of Giant Cell Tumors of Bone in Limbs: a Prospective, Single-center, Single-arm, Open Study

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18-65.
  • Biopsy confirmed giant cell tumor of bone.
  • Lesions located in the limbs.
  • This operation is the initial treatment.
  • No use of denosumab or diphosphonates before surgery.
  • Planned operation is intralesional curettage with bone cement filling.
  • Preoperative bone scan and chest CT show a single lesion without metastasis.
  • Fully understand the benefits and risks and willing to sign informed consent.
Not Eligible

You will not qualify if you...

  • Known allergy to iodine contrast, indocyanine green, or bone cement.
  • Severe liver or kidney failure.
  • Pregnant or breastfeeding.
  • Have other malignant tumors and are receiving treatment.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University People's Hospital

Beijing, Beijing Municipality, China, 100044

Actively Recruiting

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Research Team

H

Han Wang, MD

CONTACT

X

Xiaodong Tang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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