Testing Ginger and Lemon Essential Oil Inhalation to Reduce Chemotherapy Nausea in Blood Cancer Patients A Multicenter, Double-Blind Study Using Aromatherapy with Standard Treatments

What this Trial Is About

Researchers are studying how inhaled aromatherapy using a mixture of ginger and lemon essential oils can help manage nausea and vomiting caused by chemotherapy in patients with blood cancers. This study aims to see if adding this aromatherapy to standard anti-nausea treatments improves nausea scores, quality of life, and appetite during the first day of chemotherapy treatment. The trial is conducted across multiple centers with experienced medical and nursing staff coordinating the safe and scientific use of aromatherapy. Participants are randomly assigned to one of two groups one receives the usual anti-nausea treatment plus inhalation of the ginger and lemon essential oil blend, while the other receives the same standard care plus a placebo aromastick with a neutral, odorless oil. Patients will use their assigned aromastick during three chemotherapy cycles. The study uses a double-blind design to compare the effects of the inhaled aromatherapy against placebo. During the study, participants will be monitored for nausea and vomiting intensity at various times up to three months after treatment begins. Researchers will also assess quality of life, dietary intake, and the use of antiemetic medications. The study includes evaluations at one day, four days, one month, two months, and three months to gather comprehensive data on symptoms and overall well-being. The total participation period covers multiple chemotherapy cycles and follow-up assessments to understand the impact of aromatherapy on chemotherapy-induced nausea and vomiting.

Efficacy of Inhaled Aromatherapy on Nausea and Vomiting in Hematological Malignancies