Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04949087

Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)

Led by Rush University Medical Center · Updated on 2026-02-17

200

Participants Needed

1

Research Sites

250 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to compare the efficacy of intra-articular corticosteroid injections versus platelet-rich plasma injections for non-operative treatment of primary glenohumeral osteoarthritis. The efficacy of intra-articular injections, outside of hyaluronic acid, for the treatment of glenohumeral OA is not known, yet these treatments are commonly used with hopes of providing patients with symptomatic relief that can hopefully delay or prevent the need for shoulder arthroplasty. This study will help elucidate the therapeutic benefit of corticosteroid and Platelet Rich Plasma (PRP) injections in this patient population.

CONDITIONS

Official Title

Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient 18 years of age or older
  • Diagnosed primary glenohumeral arthritis confirmed by X-rays and clinical evaluation
  • Baseline pain level greater than 4 on the Visual Analog Scale
Not Eligible

You will not qualify if you...

  • Secondary arthritis causes such as septic arthritis, rheumatoid arthritis, rotator cuff arthropathy, or post-traumatic arthritis
  • Shoulder surgery on the affected side within the last year
  • Any injection in the affected shoulder joint within the past 3 months
  • Allergy to lidocaine
  • Known pregnancy
  • Current workers compensation case related to shoulder

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rush University Medical Center

Chicago, Illinois, United States, 60612

Actively Recruiting

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Research Team

C

Carla M Edwards, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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