Testing Aminophylline Instillation to Improve Ureteroscope Access for Ureteric Stone Treatment Without Balloon Dilatation

What this Trial Is About

Urolithiasis, or urinary tract stones, is a common condition worldwide with increasing prevalence in people over 30 years old. This trial investigates the use of local aminophylline instillation into the ureter during ureteroscopy, aiming to improve stone access without the need for balloon dilation. The study evaluates whether aminophylline can relax the ureter and reduce complications during stone removal procedures. Participants will initially undergo direct semi-rigid ureteroscopy without balloon dilation. If the ureteroscope cannot advance, 20 ml of aminophylline will be instilled locally through a ureteric stent. After 10 minutes, another attempt to pass the ureteroscope will be made to assess success. This method is being studied as a possible alternative to balloon dilation during ureteroscopic stone treatment. During the study, researchers will monitor the success rate of ureteral access and stone scoping from the start to the end of the procedure. They will also evaluate the complete extraction of stones. The study includes follow-up assessments related to the procedures success and safety. Participants will be involved in the procedure and monitored throughout, with the total participation duration based on the procedure timeline.

Efficacy of Intra-Ureteric Aminophylline Installation After Failed Stone Accessibility by Semi-rigid Ureteroscopy. Prospective Trial