Effect of Acetaminophen on Postoperative Percocet Use In Hip Arthroscopy: A Randomized Controlled Trial.
David A Bloom, David J Kirby, Kamali Thompson...
https://pubmed.ncbi.nlm.nih.gov/33045334Actively Recruiting
Phase 4
Age: 18Years - 89Years
All Genders
ID07037888
Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy: A Prospective Randomized Controlled Trial
Led by Henry Ford Health System · Updated on 2025-06-26
100
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating whether the medication ketorolac can manage pain after hip arthroscopy as well or better than standard opioid-based pain medications. This clinical trial focuses on adults over 18 years old undergoing hip arthroscopy for femoroacetabular impingement. The goal is to see if ketorolac can reduce pain and the need for opioid medications following surgery, potentially offering a safer pain relief option. Participants will be randomly assigned to one of two groups. The control group will receive the current standard pain management, including hydrocodone-acetaminophen, diazepam, and indomethacin. The experimental group will receive the standard protocol plus ketorolac given as an intraoperative intravenous dose and oral tablets, along with omeprazole to protect the stomach. Both groups will take their assigned medications after surgery. During the study, participants will keep a pain journal for 5 days to record their pain levels and side effects. They will also complete follow-up surveys and assessments at 2 weeks, 6 weeks, and 3 months after surgery. Researchers will measure pain using the Visual Analog Scale on post-operative day 4 and evaluate physical function and pain interference with PROMIS scores. The study monitors medication use and safety throughout the participation period, which extends to three months post-surgery.
CONDITIONS
Brief Title
Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy: A Prospective Double-Blinded Randomized Controlled Trial
Who Can Participate
Age: 18Years - 89Years
All Genders
Eligibility Criteria
You may qualify if you...
- Patients undergoing hip arthroscopy over the age of 18 with Dr. T. Sean Lynch
- Diagnosis of femoroacetabular impingement (FAI)
You will not qualify if you...
- Inability to consent and/or do not speak English
- Conditions contraindicated with NSAIDs such as medication allergy, peptic ulcer disease, bleeding diathesis, and renal disease
- History of drug and alcohol use disorder
- Chronic analgesia use (filled two opioid prescriptions within 6 months of the surgery)
- Psychotropic medication usage
- Use of pentoxifylline, probenecid, aspirin, and/or NSAIDs who cannot stop taking it for the study
- Not discharged same day after surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 5 days
Participants receive either intra-operative IV and oral doses of Ketorolac plus standard pain management or the standard care pain protocol after hip arthroscopy.
Daily medication starting post-operative day 0
Follow-up
Duration - 3 months
Participants are assessed for physical function and pain interference at 2 weeks, 6 weeks, and 3 months after surgery.
3 visits (in-person) at 2 weeks, 6 weeks, and 3 months
Trial Site Locations
Total: 1 location
1
Henry Ford Health
Detroit, Michigan, United States, 48202
Actively Recruiting
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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Toufic R Jildeh, Muhammad J Abbas, Laith Hasan...
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Collin LaPorte, Michael D Rahl, Olufemi R Ayeni...
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Edward C Beck, Benedict U Nwachukwu, Kyleen Jan...
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