Hip arthroscopy: Indications, outcomes and complications.
Mujahid Jamil, Wael Dandachli, Shahryar Noordin...
https://pubmed.ncbi.nlm.nih.gov/28823795/Actively Recruiting
Led by Henry Ford Health System · Updated on 2026-06-30
100
Participants Needed
1
Research Sites
13 weeks
Total Duration
Researchers are evaluating whether ketorolac can manage pain after hip arthroscopy as well or better than standard opioid-based pain medications. The study focuses on adults over 18 years old undergoing hip arthroscopy for femoroacetabular impingement. Participants include both men and women who can consent and communicate in English. The trial aims to see if ketorolac reduces pain and the need for opioids after surgery. Participants are randomly assigned to one of two groups. The control group receives the standard pain management protocol including hydrocodone-acetaminophen, diazepam, and indomethacin. The experimental group receives ketorolac during surgery plus oral ketorolac and omeprazole after surgery, alongside the standard protocol. Medication is started on the day of surgery and continued as prescribed. Participants will take their assigned medications after discharge and keep a pain journal for 5 days, recording pain and side effects. They will complete follow-up surveys and assessments at 2 weeks, 6 weeks, and 3 months post-surgery. Researchers will measure pain using the Visual Analog Scale on day 4, track opioid use, and assess physical function and pain interference using PROMIS scores. The study monitors participants for up to 3 months to evaluate pain control and medication use.
CONDITIONS
Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy
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Henry Ford Health System
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Ketorolac plus Standard Pain Medications | Standard Pain Medications Only | Multimodal Non-Opioid Pain Management Protocol |
|---|---|---|---|
| What It Is | Addition of ketorolac, an intravenous nonsteroidal anti-inflammatory drug (NSAID), alongside standard pain medications prescribed after hip arthroscopy. | Postoperative pain management using hydrocodone-acetaminophen, indomethacin, diazepam, and omeprazole, without ketorolac. | A pain management protocol that prioritizes non-opioid medications (NSAIDs, acetaminophen) and minimizes or avoids routine opioid use after hip arthroscopy. |
| Role in Trial | Investigational arm testing ketorolac as an adjunct to standard postoperative pain medications. | Control arm receiving the usual postoperative pain regimen without ketorolac. | Contextual comparator summarizing guideline-supported practices prioritizing multimodal, non-opioid pain management after hip arthroscopy. |
| Primary Use | Intended to reduce postoperative pain and potentially decrease reliance on opioids after hip arthroscopy. | Standard prescription for pain after hip surgery, combining opioid and non-opioid medications as needed. | Regular management of pain after hip arthroscopy using NSAIDs and acetaminophen, aiming for effective pain relief while minimizing opioid exposure. |
| How It Is Given or Performed | Ketorolac is administered intravenously during surgery, followed by oral doses every 6 hours beginning on the day of surgery. | Pain medications are prescribed based on patient need for oral administration starting on the day of surgery. | NSAIDs and acetaminophen are administered orally, often scheduled rather than as-needed; opioids are either limited or omitted. |
| Evidence Status | Ketorolac's efficacy as an adjunct postoperative analgesic is under active investigation in this randomized trial for pain relief and opioid use reduction. | Standard regimen efficacy is established through routine clinical use and published studies on postoperative pain management after hip arthroscopy. | Multimodal non-opioid protocols have demonstrated effective pain control and lower opioid use in recent prospective trials after arthroscopic surgery. |
| Important Limitations | Ketorolac may carry risks including bleeding, gastrointestinal discomfort, and contraindications for certain patients; long-term safety for routine post-arthroscopy use is not yet fully established. | Standard regimens using opioids can increase risk of dependence, sedation, gastrointestinal effects, and are not suitable for all patients; NSAIDs, benzodiazepines, and other agents may have their own contraindications. | While multimodal opioid-sparing protocols offer advantages, NSAIDs may be contraindicated for patients with history of gastrointestinal, renal, or bleeding disorders, and evidence for optimal regimen in hip arthroscopy populations continues to evolve. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 5 days
Participants receive either ketorolac plus standard opioid pain medications or standard opioid pain medications alone after hip arthroscopy surgery.
Daily medication and pain journal entries
Duration - 3 months
Participants complete follow-up surveys and assessments about pain and physical function at 2 weeks, 6 weeks, and 3 months after surgery.
3 follow-up visits or surveys
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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https://pubmed.ncbi.nlm.nih.gov/28258773/Henry Ford Health System
Lead Sponsor