Actively Recruiting
Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults
Led by University of Santo Tomas · Updated on 2026-05-04
60
Participants Needed
1
Research Sites
23 weeks
Total Duration
On this page
Sponsors
U
University of Santo Tomas
Lead Sponsor
Y
Yakult Honsha Co., LTD
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary purpose of this study is to investigate whether the consumption of a probiotic drink (with Lacticaseibacillus paracasei strain Shirota (LcS)) relieves constipation-related symptoms of Filipino adults, specifically its effect on stool consistency, frequency, and duration, and on gastrointestinal discomfort.
CONDITIONS
Official Title
Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Filipino adult male or female aged 18 to 59 years old
- Apparently healthy adults with constipation-related symptoms of hard to lumpy stools (Bristol Stool Form Scale 1-2) in 25% or more of defecations in a week
- With cold storage at home
You will not qualify if you...
- Habitual intake of food items containing probiotics and prebiotics as food supplements in the previous 3 months at least three times per week
- Constipation due to organic or neurologic origin
- High fiber intake (over 30 g/day)
- Pregnant or lactating
- Allergy to dairy products and/or lactose intolerance
- Use of laxatives, anticholinergics, or medications for constipation or diarrhea within the past three months
- Use of antibiotics within the past two weeks
- Presence of chronic diseases such as diabetes mellitus and its complications, cardiovascular diseases, or kidney problems
- Gastrointestinal conditions that may interfere with outcome evaluation such as hemorrhoids, intestinal obstruction, or inflammatory bowel diseases
- Recent history of any gastrointestinal surgery
- Pre-existing medical conditions like hypo- or hyperthyroidism and congenital abnormalities
- Participation in another study with test product within two months prior to this study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Santo Tomas
Manila, Manila, Philippines, 1015
Actively Recruiting
Research Team
D
Diane S Mendoza-Sarmiento, Ph.D
CONTACT
N
Nicole Kate D Sison, MS in Food Science
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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