Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06540651

Efficacy of Light Therapy in Treatment of Chronic Cluster Headache

Led by Assistance Publique Hopitaux De Marseille · Updated on 2025-03-17

48

Participants Needed

2

Research Sites

116 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cluster headache is a primary headache. The chronic form of the disease is often difficult to treat. It is now considered a chronobiological disease. This chronobiological character is based on clinical, biological and radiological arguments. This study focuses on the use of light therapy in cluster headache. Light therapy has already been used in the treatment of other chronobiological diseases, such as seasonal depression, but also recently in the therapy of other primary headaches (such as migraine). Its aim is to re-adjust chronobiological rhythms, and it therefore seems worth testing in the chronic form of cluster headache. Light therapy is delivered to the patient using a consumer electronics device.The main objective is to evaluate the prophylactic efficacy of light therapy in patients with chronic cluster headache.

CONDITIONS

Official Title

Efficacy of Light Therapy in Treatment of Chronic Cluster Headache

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female, 18 years old or more
  • Diagnosis of chronic cluster headache according to ICHD-3 criteria
  • At least 24 cluster headache seizures during baseline
  • Stable prophylactic treatment for at least 1 month with commitment not to change it during the study
  • Affiliated with the French social security system
  • Understands and speaks French correctly
  • Provided free and informed written consent
Not Eligible

You will not qualify if you...

  • Contraindication to light therapy or use of photosensitizing treatment
  • History of eye diseases such as cataract, macular degeneration, glaucoma, retinitis pigmentosa
  • Working night shifts
  • Other neurological, psychiatric, or developmental disorders incompatible with the study
  • Current treatment of cluster headache with melatonin
  • Pregnant or breastfeeding women, persons deprived of liberty by judicial decision, socially vulnerable persons, or adults unable to give consent

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Hopital La Timone

Marseille, France, 13005

Actively Recruiting

2

Hôpital de Cimiez

Nice, France, 06000

Not Yet Recruiting

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Research Team

A

Anne DONNET

CONTACT

S

Sophie Tardoski

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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