Study on Light Therapy to Prevent Chronic Cluster Headache Attacks Using Luminette Devices

What this Trial Is About

Cluster headache is a primary headache condition, with its chronic form often being hard to treat. This research investigates the use of light therapy, which has been applied in other chronobiological disorders like seasonal depression and migraine, to see if it can help reset biological rhythms and reduce chronic cluster headache attacks. The study is a proof-of-concept trial aimed at assessing the preventive effects of light therapy in patients with chronic cluster headache. Participants will use Luminette4 devices that emit light in different spectra. One group will receive active light therapy with wavelengths between 400 and 750 nm, while the control group will use a device emitting light between 560 and 650 nm, which is assumed to have no therapeutic effect. This treatment is delivered using a consumer electronics device and is randomized and double-blinded to compare the effects of the two light therapies. During the study, participants will be monitored for their weekly number of cluster headache attacks at day 28, along with daily reports of headache intensity, use of acute treatments, and any adverse reactions. Participants will also complete a Patients Global Impression of Change score at day 28. The trial includes close assessment of safety and efficacy, with the total participation lasting at least 28 days of treatment and monitoring.

Efficacy of Light Therapy in Treatment of Chronic Cluster Headache