Testing a 12-Week Multicomponent Intervention to Improve Cognitive Function in Older Adults with Mild Cognitive Impairment and Their Caregivers

What this Trial Is About

Researchers are investigating a multicomponent intervention aimed at improving cognitive function in older adults with mild cognitive impairment and their primary caregivers. This condition is a precursor to dementia and poses risks to both patients and their caregivers, often family members without formal training. The study is a pilot randomized clinical trial designed to generate evidence on the interventions efficacy and applicability, tailored specifically to the Colombian population. The intervention lasts 12 weeks and combines cognitive training, physical exercise, and nutritional counseling for patients, delivered at home twice a week by professionals, along with a recommendation to walk 30 minutes daily. Caregivers participate in weekly group sessions led by healthcare professionals to support their caregiving role. The control group receives usual care, including cognitive rehabilitation and physical therapy, plus educational materials on infectious diseases sent weekly. Participants and their caregivers will be assessed at baseline and followed up at 3, 6, and 9 months. Evaluations include cognitive function tests covering multiple domains, physical frailty, nutritional status, mobility, independence, social support, and caregiver burden. Additionally, a subsample will have their intestinal microbiota composition and APOE gene allele status analyzed before and after the intervention. Attendance and adherence to sessions will be monitored to ensure study compliance.

Efficacy of a Multicomponent Intervention on Cognitive Function for the Caregiver-patient Dyad