Actively Recruiting

Phase Not Applicable
Age: 0 - 18Years
All Genders
NCT07086144

Efficacy of a Myocardial Panel in the Management and Treatment of Pediatric Myocarditis

Led by Azienda Ospedaliero, Universitaria Ospedali Riuniti · Updated on 2025-07-25

30

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to determine the efficacy a of combined management and treatment driven by the systematic determination of viral genome, bacterial serology, and markers of inflammation in pediatric patients (\< 18 years old) diagnosed with myocarditis complicated by arrhythmias (supraventricular and ventricular tachycardias and heart block) or ventricular dysfunction (left ventricular ejection fraction \< 50% or right ventricular fractional area change \< 35%). The main question it aims to answer is: Does this panel help resolve arrhythmias or myocardial dysfunction due to myocarditis during hospitalisation and follow-up? Researchers will compare patients managed and treated in 2024 without applying the myocarditis panel with those enrolled in 2025 who received the panel. Arrhythmias and myocardial dysfunction will be managed in accordance with recent guidelines. Antiviral, antibiotic or immunosuppressive therapies will be implemented in addition to standard therapy when required by the panel.

CONDITIONS

Official Title

Efficacy of a Myocardial Panel in the Management and Treatment of Pediatric Myocarditis

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pediatric patients younger than 18 years old
  • Diagnosed with myocarditis complicated by arrhythmias
  • Diagnosed with myocarditis complicated by myocardial dysfunction
Not Eligible

You will not qualify if you...

  • Parents or legal guardians refuse consent for study participation
  • Myocarditis without arrhythmias or myocardial dysfunction

AI-Screening

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Trial Site Locations

Total: 1 location

1

Francesco Bianco

Ancona, The Marches, Italy, 60126

Actively Recruiting

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Research Team

F

Francesco Bianco, M.D., Ph.D., MSc, FEACVI

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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