Actively Recruiting
Efficacy of Nerve Block Versus Botox in Chronic Migraine Management
Led by Zagazig University · Updated on 2024-11-12
64
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine whether nerve block injections (specifically, supratrochlear and greater occipital nerve injections) are as effective as Botulinum toxin A (Botox) injections in treating chronic migraine in adults. The main questions it aims to answer are: * Do nerve block injections reduce the number of monthly migraine days compared to baseline? * Are there any differences in the frequency of migraine-related symptoms between the nerve block and Botox treatment groups? * Which treatment leads to higher patient satisfaction and improved quality of life? Participants in this study will: * Receive either nerve block injections or Botox injections every 12 weeks. * Visit the clinic once every month for follow-ups and assessments. * Maintain a headache diary to record the frequency and severity of their migraines and any adverse effects experienced. * Researchers will compare the outcomes of the two groups to determine if one treatment is superior in terms of efficacy and patient satisfaction.
CONDITIONS
Official Title
Efficacy of Nerve Block Versus Botox in Chronic Migraine Management
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 65 years
- Diagnosis of chronic migraine with headaches on 15 or more days per month for over 3 months, including at least 8 migraine days
- Ability to give informed consent and follow study procedures
- No changes in preventive migraine medications in the past 3 months
You will not qualify if you...
- Allergy or sensitivity to local anesthetics or Botulinum toxin
- Previous nerve block or Botox treatment within the last 6 months
- Significant psychiatric or neurological disorders affecting study participation
- Pregnancy or breastfeeding
- Contraindications to either treatment based on product guidelines
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zagazig University, Faculty of Medicine
Zagazig, Sharqia Province, Egypt, 44519
Actively Recruiting
Research Team
A
Ahmed A Bessar, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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