Study on Silver-Coated Prosthesis to Lower Infection Risk After Joint Replacement Surgery

What this Trial Is About

Researchers are investigating a new prosthesis coated with bacteriostatic silver to see if it can reduce infections that occur around joint implants after surgery. These infections, called periprosthetic joint infections, are serious complications leading to many revision surgeries, especially in patients at higher risk like the elderly, diabetics, immunocompromised individuals, or those with prior infections. This observational study aims to understand whether the silver coating effectively lowers the occurrence of these infections. The study involves patients receiving either a prosthesis with the silver coating or one without it. Participants include those awaiting second-stage surgery after an infection or patients scheduled for primary prosthetic surgery who have recurrent infections in other body areas. Researchers will monitor patients over time to compare infection rates and safety of the silver-coated devices. Throughout the study, participants will have follow-up assessments at 1, 3, 6, 12, and 24 months after surgery. These visits will evaluate the number of infections, safety profiles of the silver coating, clinical scores related to patient outcomes, integration of the implant, and any complications. The goal is to gather detailed information on how well the silver-coated prosthesis performs in preventing infections and ensuring patient safety over two years.

Efficacy of New Silver-coated Prosthesis in Reducing the Incidence of Periprosthetic Infections