Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06802354

Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery

Led by Jelena Krunic · Updated on 2025-01-31

20

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if use of ozone works to treat complications after impacted mandibular third molar surgery. It will also learn does ozone has positive effect on wound healing and quality of life. The main questions it aims to answer are: * Does ozone reduce incidence of postoperative compliactions such as pain, swelling or reduced mouth opening after impacted mandibular third molar surgery? * Does ozone improve wound healing after impacted mandibular third molar surgery? * Does ozone have positive effect on quality of life after impacted mandibular third molar surgery? Participants will: * Receive ozone after impacted mandibular third molar surgery. * Visit the clinic 1st, 3rd, and 7th days after the intervention for checkups and tests. * Keep a diary of their symptoms.

CONDITIONS

Official Title

Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years
  • Patients with bilaterally impacted mandibular third molars classified as impaction index II B
  • Patients in good general health (ASA classification I or II)
Not Eligible

You will not qualify if you...

  • Contraindications for ozone application including pregnancy, hyperthyroidism, favism, anemia, myasthenia, bleeding disorders, alcohol intoxication, myocardial infarction, pacemaker, or allergy to ozone
  • Use of corticosteroid or antibiotic therapy in the last three months
  • Signs of local inflammation in the oral cavity
  • Female patients who are pregnant or breastfeeding

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

University of East Sarajevo, Faculty of Medicine

Foca, Republika Srpska, Bosnia and Herzegovina, 73300

Actively Recruiting

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Research Team

J

Jelena Krunic, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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