Actively Recruiting
Efficacy of a Photosynthetic Dermal Matrix for the Treatment of Full-Thickness Skin Wounds
Led by Pontificia Universidad Catolica de Chile · Updated on 2025-09-05
20
Participants Needed
1
Research Sites
148 weeks
Total Duration
On this page
Sponsors
P
Pontificia Universidad Catolica de Chile
Lead Sponsor
H
Hospital del Trabajador de Santiago
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate whether the incorporation of photosynthetic microalgae into scaffolds for dermal regeneration improves healing outcomes in adult patients with acute and cronic full-thickness skin wounds. The primary objectives are to determine whether the use of photosynthetic scaffolds enhances wound granulation and reduces infection rates compared to standard dermal regeneration scaffolds. Additionally, the quality of the regenerated skin will be assessed and compared between treatment types. Participants will: * Receive treatment with either standard dermal regeneration scaffolds or identical scaffolds containing photosynthetic microalgae. These treatments will be applied either to randomly assigned areas of the same wound or to different wounds on the same patient. * Undergo regular follow-up assessments to monitor wound healing progress, infection rates, graft integration, and the qualiy of the regenerated skin. * Complete self-assessment questionnaires regarding their experience and perceived outcomes.
CONDITIONS
Official Title
Efficacy of a Photosynthetic Dermal Matrix for the Treatment of Full-Thickness Skin Wounds
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older
- Covered by social insurance law or under the "Complementary Service Sales" (VSC) program
- Presence of full-thickness skin wounds
- Wounds with homogeneous granulation tissue
- Wound size between 25 cm² and 200 cm²
- Signed informed consent to participate in the study
You will not qualify if you...
- History of psychiatric disorder impairing decision-making or treatment adherence
- Presence of acute medical condition unrelated to the wound at enrollment
- Wounds with exposed bone, tendon, or major blood vessels
- Psychosocial conditions hindering adherence to study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital del Trabajador
Santiago, RM, Chile, 7501239
Actively Recruiting
Research Team
A
Anil Sadarangani, PhD, MBA
CONTACT
J
José Tomás Egaña, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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