Actively Recruiting

Phase 2
Age: 18Years +
All Genders
Healthy Volunteers
NCT07157657

Efficacy of a Photosynthetic Dermal Matrix for the Treatment of Full-Thickness Skin Wounds

Led by Pontificia Universidad Catolica de Chile · Updated on 2025-09-05

20

Participants Needed

1

Research Sites

148 weeks

Total Duration

On this page

Sponsors

P

Pontificia Universidad Catolica de Chile

Lead Sponsor

H

Hospital del Trabajador de Santiago

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate whether the incorporation of photosynthetic microalgae into scaffolds for dermal regeneration improves healing outcomes in adult patients with acute and cronic full-thickness skin wounds. The primary objectives are to determine whether the use of photosynthetic scaffolds enhances wound granulation and reduces infection rates compared to standard dermal regeneration scaffolds. Additionally, the quality of the regenerated skin will be assessed and compared between treatment types. Participants will: * Receive treatment with either standard dermal regeneration scaffolds or identical scaffolds containing photosynthetic microalgae. These treatments will be applied either to randomly assigned areas of the same wound or to different wounds on the same patient. * Undergo regular follow-up assessments to monitor wound healing progress, infection rates, graft integration, and the qualiy of the regenerated skin. * Complete self-assessment questionnaires regarding their experience and perceived outcomes.

CONDITIONS

Official Title

Efficacy of a Photosynthetic Dermal Matrix for the Treatment of Full-Thickness Skin Wounds

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older
  • Covered by social insurance law or under the "Complementary Service Sales" (VSC) program
  • Presence of full-thickness skin wounds
  • Wounds with homogeneous granulation tissue
  • Wound size between 25 cm² and 200 cm²
  • Signed informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • History of psychiatric disorder impairing decision-making or treatment adherence
  • Presence of acute medical condition unrelated to the wound at enrollment
  • Wounds with exposed bone, tendon, or major blood vessels
  • Psychosocial conditions hindering adherence to study protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital del Trabajador

Santiago, RM, Chile, 7501239

Actively Recruiting

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Research Team

A

Anil Sadarangani, PhD, MBA

CONTACT

J

José Tomás Egaña, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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