Actively Recruiting
Efficacy in Preventing Hypertrophic Scars: A Randomised Controlled Trial Comparing Chitosan Cream, Silicone Gel & Olive Oil
Led by Universiti Sains Malaysia · Updated on 2026-01-02
120
Participants Needed
3
Research Sites
45 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the efficacy of three different topical applications in preventing hypertrophic scars in adults with scars healed after suturing. The main question it aims to answer is: Is Chitosan cream effective in preventing hypertrophic scars? Researchers will compare Chitosan cream with silicone gel and olive oil to see if there is any difference in their efficacies. Participants will be randomly assigned to three groups, with each group using a different topical application. They will be instructed to: * apply the topical application on their scar twice a day for 8 weeks * attend follow-up visits at 4, 12 and 24 weeks for a doctor to assess their scar and take clinical photographs * immediately inform the researcher if they experience any side effects
CONDITIONS
Official Title
Efficacy in Preventing Hypertrophic Scars: A Randomised Controlled Trial Comparing Chitosan Cream, Silicone Gel & Olive Oil
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with traumatic or surgical wounds which have healed by primary intention within 14 days
- Length of scar at least 3cm
You will not qualify if you...
- Patients with seafood allergy
- Patients with scar from wounds that were complicated by infection or wound breakdown
- Patients who have undergone scar treatment by other modalities
- Patients with history of keloids / hypertrophic scars
- Pregnant patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Hospital Raja Perempuan Zainab II
Kota Bharu, Kelantan, Malaysia, 15586
Not Yet Recruiting
2
Hospital Pakar Universiti Sains Malaysia
Kubang Kerian, Kelantan, Malaysia, 16150
Actively Recruiting
3
Hospital Kuala Lumpur
Kuala Lumpur, Kuala Lumpur, Malaysia, 50586
Not Yet Recruiting
Research Team
E
Esther HM Tan, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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